In a market driven by constant innovation, new ways of approaching skin ageing continue to emerge. Among them, one concept has been gaining increasing attention from both experts and consumers: skin longevity.

What is "skin longevity?

Skin longevity represents a shift in perspective, moving from a primarily corrective approach, focused on reducing visible signs of ageing, to a more preventive one, aimed at maintaining skin health and a youthful appearance over time. It is not defined by a single ingredient, product, or treatment. Rather, it is a long-term approach built on consistency, prevention, and scientific understanding. Lifestyle habits, environmental aggressors, and daily skincare routines - all play an important role in how the skin ages.

One of the scientific fields that has most contributed to advancing this understanding is epigenetics. By studying how external factors such as sun exposure, pollution, and lifestyle can influence the expression of our genes, epigenetics has opened new perspectives on the biological mechanisms associated with skin ageing and longevity.

These discoveries have also helped explain why two people of the same chronological age can show very different signs of skin ageing. While chronological age refers to the number of years we have lived, biological age reflects how our skin has actually aged over time.

The Eucerin Hyaluron-Filler + Longevity range

It is within this context that Eucerin Hyaluron-Filler + Longevity was developed. Inspired by the latest advances in epigenetics research, the range was designed to support a more comprehensive approach to skin ageing and help address the mechanisms associated with skin longevity.

The pursuit of a deeper understanding of skin longevity led Beiersdorf to develop Age Clock Technology, the first biological clock specifically designed for the skin. [1,2] This patented innovation allows the measurement of biological skin age and helps identify ingredients capable of supporting the skin's longevity mechanisms. One of the most significant discoveries was Epicelline®, now the signature ingredient of the Eucerin Hyaluron-Filler + Longevity range. By acting on epigenetic mechanisms associated with skin ageing, it helps support skin longevity and a more youthful-looking appearance over time.

The Eucerin Hyaluron-Filler + Longevity range was developed to support a more holistic approach to skin ageing. By combining Epicelline® with ingredients such as Hyaluronic Acid, Glycine Saponin and Enoxolone, the formulas help address multiple dimensions of skin ageing, from hydration and firmness to radiance, skin smoothness and wrinkle volume.

The Eucerin Hyaluron-Filler + Longevity routine

One of the key principles of skin longevity is consistency. Reflecting this philosophy, the Eucerin Hyaluron-Filler + Longevity range combines the Epigenetic Serum, featuring the highest concentration of Epicelline®, with the Day Cream SPF30 and the Night Cream, creating a complete day-to-night approach to skin ageing.

While the Day Cream SPF30 combines daily care with UV protection in a lightweight texture, the Night Cream, enriched with Provitamin B5, supports overnight skin regeneration and provides comfort through its nourishing texture.

The routine can be further complemented with Eucerin Sun Photoaging Control Fluid SPF50+, a lightweight, fragrance-free sunscreen enriched with Hyaluronic Acid.

Beyond daily skincare, the Eucerin Hyaluron-Filler + Longevity routine can also complement aesthetic procedures. Together, these products help address 12 signs of ageing, and clinical studies have demonstrated the ability of this approach to act directly on biological skin age, helping reverse it by up to 5 years. [3,4]

More than an anti-ageing range, Eucerin Hyaluron-Filler + Longevity embodies the principles of skin longevity, combining scientific innovation and daily care to help skin look healthier and more youthful for longer.


[1] Bormann F et al. Reduced DNA methylation patterning and transcriptional connectivity define human skin aging. Aging Cell. 2016 Jun

[2] Bienkowska A et al, Development of an epigenetic clock to predict visual age progression of human skin. Front Aging. 2024 Jan 11;4:1258183.

[3] Clinical study after 2 and 4 weeks involving 41 and 56 volunteers, respectively.

[4] Clinical study after 8 weeks involving 60 volunteers, with twice-daily application of the Epigenetic Serum. Biological skin age determined using Age Clock Technology.